Research

Expanding knowledge and improving outcomes

We fund innovative research projects in the UK, typically in partnership with other institutions,  that expand knowledge, improve patient outcomes and pioneer new forms of orthopaedic treatment. We  focus on research projects that are capable of rapid translation, either by creating new MSK solutions (innovative products and services) or improving clinical practices and processes.

These are our recent research projects:

Research

A precision health approach to osteoarthritis: early diagnosis, stratification and risk prediction using state-of-the-art machine learning models.

Posted on: 28-03-2025
The aim of this research is to develop novel precision health tools for the early diagnosis, progression prediction, stratification and, eventually, management of osteoarthritis.
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Research

Establishing the feasibility of real world surveillance of orthopaedic devices using routinely collected data.

Posted on: 28-03-2025
The research is establishing the feasibility of orthopaedic implant safety surveillance, using longitudinal data linked between the feasibility of orthopaedic implant safety surveillance.
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Research

Improving Wrist Injury Pathways (I-WIP)

Posted on: 28-03-2025
The researchers are seeking to improve care for patients with wrist injuries by helping NHS hospitals introduce early MRI more effectively.
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Research

Development of a diagnostic protocol to aid the investigation and management of posterior malleolus ankle fractures.

Posted on: 28-03-2025
This research project aims to improve patient outcomes and reduce the cost of investigating and treating these fractures by developing a diagnostic protocol to help surgeons manage such a complex ankle fracture.
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Research

Torque visuo-motor feedback training: A new way to manage patellar tendinopathy.

Posted on: 28-03-2025
This research aims to evaluate the effectiveness of a novel training intervention for managing patellar tendinopathy and seeks to identify the underlying mechanisms that contribute to motor function impairments to determine whether these can be ameliorated through the proposed treatment.
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Research

Identifying objective measures of sex-specific pain in humans that can be used diagnostically to target treatment.

Posted on: 28-03-2025
The researchers aim to identify signals that drive pain and bone remodelling in human osteoarthritis and determine how these differ between males and females and pre and post menopause.
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Research

Development and feasibility of a digital health intervention to encourage exercise maintenance after end of falls prevention exercise programmes

Posted on: 28-03-2025
The researchers aim to design and investigate the feasibility, acceptability, and safety of a digitally supported exercise maintenance intervention to Falls Management Exercise (FaME) programme service-users.
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Research

Mesenchymal stromal cells in cartilage regeneration: defining the immunomodulatory characteristics on macrophage populations

Posted on: 27-03-2025
This research seeks to understand cell behaviour in order to develop new treatments for joint cartilage injury.
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Research

Surgical treatment of pathological posterior medial meniscal extrusion: A biomechanical study comparing centralization techniques.

Posted on: 27-03-2025
Comparing the commonest centralization techniques biomechanically on animal knee joints, the aim of this project is to see which technique is the most effective in keeping both the meniscus rooted down at its periphery and the kinematics of the knee as close to a healthy one.
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